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促红细胞生成素通过减少细胞浸润减轻小鼠心肌缺血再灌注损伤 被引量:7

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摘要 促红细胞生成素(EPO)具有抗心肌缺血再灌注损伤的作用,研究多从分子水平研究其作用机制。我们通过观察缺血再灌注后细胞浸润及其表达损伤因子的情况,探讨炎性细胞在EPO干预后对心肌细胞的影响。
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2013年第10期2230-2230,共1页 Chinese Journal of Experimental Surgery
基金 国家自然科学基金资助项目(812600561
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  • 1李灿,陈瑛,洪明玉.促红细胞生成素预处理对大鼠急性缺血再灌注肾的保护作用[J].中国病理生理杂志,2004,20(12):2336-2338. 被引量:3
  • 2Li F,Chong ZZ,Maiese K.Erythropoietin on a tightrope:balancing neuronal and vascular protection between intrinsic and extrinsic pathways[J].Neurosignals,2004,13(6):265-289.
  • 3Silva M,Benito A,Am C,et al.Erythropoietin can induce the expression of bcl-XL through stat5 in erythropoietin-dependent progenitor cell lines[J].J Biol Chem,1999,274(32):22165-22169.
  • 4Tramontano AF,Muniyappa R,Black AD,et al.Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway[J].Biochem Biophys Res Commun,2003,308(4):990-994.
  • 5Liu X,Xie W,Liu P,et al.Mechanism of the cardioprotection of rh-EPO pretreatment on suppressing the inflammatory response in ischemia reperfusion[J].Life Sci,2006,78(19):2255-2264.
  • 6Li YW,Takemura GZ,Okada H,et al.Reduction of inflammatory cytokine expression and oxidative damage by erythropoietin in chronic heart failure[J].Cardiovasc Res,2006,71(4):684-694.
  • 7Sakanaka M,Wen TC,Matsuda S,et al.In vivo evidence that erythropoietin protects neurons from ischemic damage[J].Poc Natl Acad Sci,1998,95(8):4635-4640.
  • 8Noyan T,Onem O,Ramazan SM,et al.Effects of erythropoietin and pemoxifylline on the oxidant and antioxidant systems in the experimental short bowel syndrome[J].Cell Biochem Funct,2003,21(1):49-54.
  • 9Jaquet K,Krause K,Tawakol Khedal M,et al.Erythropoietin and VEGF exhibit equal angiogenic potential[J].Microvasc Res,2002,64(2):296-333.
  • 10Nishiya D,Omura T,Shimada K,et al.Effects of erythropoietin on cardiac remodeling after myocardial infarction[J].Pharmacol Sci,2006,101(1):31-39.

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  • 1Rodrigo Estévez-Loureiro,ángela López-Sainz,Armo Pérez de Prado,Carlos Cuellas,Ramón Calvio Santos,Norberto Alonso-Orcajo,Jorge Salgado Fernández,Jose Manuel Vázquez-Rodríguez,Maria López-Benito,Felipe Fernández-Vázquez.Timely reperfusion for ST-segment elevation myocardial infarction:Effect of direct transfer to primary angioplasty on time delays and clinical outcomes[J].World Journal of Cardiology,2014,6(6):424-433. 被引量:6
  • 2马兰香,高晖,赵新国,张清,贾国良,张荣庆,王岚.高、低剂量极化液对缺血/再灌注心肌细胞凋亡及相关基因的影响[J].心脏杂志,2004,16(5):427-430. 被引量:5
  • 3Jie YU,Hai-feng ZHANG,Feng WU,Qiu-xia LI,Heng MA,Wen-yi GUO,Hai-chang WANG,Feng GAO.Insulin improves cardiomyocyte contractile function through enhancement of SERCA2a activity in simulated ischemia/reperfusion[J].Acta Pharmacologica Sinica,2006,27(7):919-926. 被引量:8
  • 4Rong S,Hueper K,Kirsch T,et al.Renal PKC-epsilon deficiency attenuates acute kidney injury and ischemic allograft injury via TNF-alpha-dependent inhibition of apoptosis and inflammation[J].Am J Physiol Renal Physiol,2014,307(6):F718-F726.
  • 5Ham A,Kim M,Kim JY,et al.Selective deletion of the endothelial sphingosine-l-phosphate 1 receptor exacerbates kidney ischemia-reperfusion injury[J].Kidney Int,2014,85 (4):807-823.
  • 6IIont MA, Hungedord DS, Maryland B. Current concepts review: non- trammlle avascular necrosis of the femoral head [ J ]. J Bone Jonint Surg (Am), 1995,77 (6) :459-468.
  • 7Yassunaga Y, Hisatome T, Ikuta 3( ,et al. A historical study of the nec- rotic area after tmnstrochanteric anteric anterior rotational osteotomy for osteonecrosis of the femora] head[ J]. J Bone Joint Surg Br,2001, 83(2) :167-170.
  • 8Conzemius sr, Lauber S,Lauber HJ,et al. High-energy shock wave treatment of femoral head necerosis in adults [ J ]. Clin Orthop Relat Res,2001 ,(387) :119-126.
  • 9Rong R,Xijun X.Erythropoietin pretreatment suppresses inflammation by activating the PI3K/Akt signaling pathway in myocardial ischemia- reperfusion injury [J].Exp Ther Med,2015 ,10(2):413-418.
  • 10Heusch G,Boengier K,Schulz R.Gardio protection:nitric oxide,pro- tein kinases,and mitochondria[J].Circulation ,2008 ,118(19):1915-1919.

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