土大黄研究进展

Research Progress in Rumex Obtusifolius L.

综述了土大黄古籍文献、临床应用及现代药理研究品种,发现土大黄古籍文献、临床应用品种较少,主要集中在羊蹄、尼泊尔酸模、钝叶酸模,用于止血、抗炎、治疗皮肤病。现代药理研究品种较多,其中羊蹄、巴天酸模研究最多,其次是钝叶酸模、皱叶酸模、尼泊尔酸模,具有抗菌、止血、保肝、降糖、抗炎、抗肿瘤、治疗皮肤病等作用。但仍缺乏药理研究相应的临床应用和古籍文献记载,临床应用部分单味药和大多复方制剂仍缺乏品种鉴定或品种标注。

Rumex varieties of ancient hterature,chnical application and modem pharmacological research were reviewed in this article. It is found that less varieties of ancient documents and clinical application of Rumex exists, and they mainly focus on R. japonicus Houtt., R. obtusifolius L., R. nepalensis Spreng., and used for Hemostasis, anti-inflammatory, treatment of skin diseases. There are kinds of modem pharmacological researches, most of which are R. japonicus Houtt., Rumex patientia L. and then R. obtusifolius L., Rumex crispus L., R.nepalensis Spreng., and they can be used as antimicrobial, hemostasis, liver protection, hypoglycemic action, anti- inflammatory, anti-cancer, treatment of skin diseases. But the corresponding clinical application, and ancient literature on the pharmacological research are still not enough. Identification and labeling of varieties for clinical application of few single herbs and most of the compound preparations are still insufficient.