摘要
目的 :探讨选择性动脉内化疗在中、晚期鼻咽癌综合治疗中的应用价值。方法 :选择70例局部中、晚期鼻咽癌初治患者 ,随机分成二组(各35例) ,分别进行选择性动脉化疗(IACT)加放疗和全身化疗(SCT)加放疗 ,并采用配对的方法选择同期单纯放疗(RT)的鼻咽癌患者作为对照组 ,于放疗后对三组的疗效进行比较。结果 :IACT组完全缓解率及2年局控率为65.7%及82.9% ,SCT组为54.3%及77.1% ,RT组为42.9 %及51.4 %。结论 :选择性动脉内化疗加放疗治疗中、晚期鼻咽癌 ,短期疗效显著 。
Objective:To evaluate the clinical value of selective arterial chemotharapy and radiotherapy in treating the advanced nasopharyngeal carcinoma.Methods:Seventy patients with advanced nasopharyngeal carcinoma (stage Ⅲ or Ⅳ) were randomized to receive either combined selective arterial chemotharapy and radiotherapy (IACT group,35 patients) or combined general intravenous chemotherapy and radiotherapy (SCT group,35 patients).The patients in another control group were treated with conventional radiotherapy (RT group,35 patients) alone.After radiotherapy,the effects of three methods were compared.Results:The complete response rate and the 2 year local disease contral rate were 65.7% and 82.9% in IACT,54.3% and 77.1% in SCT,42.9% and 51.4% in RT.Conclusion:The short term therapeutic effect of selective arterial chemotherapy combined with radiotherapy on advanced nasopharyngeal carcinoma was obvious,the side effects were slight.
出处
《四川肿瘤防治》
2000年第4期217-219,共3页
Sichuan Journal of Cancer Control
关键词
鼻咽癌
动脉化疗
放疗
Nasopharyngeal carcinoma
Intraarterial chemotherapy
Radiother
