摘要
1例81岁男性患者,因肺丝状真菌感染,静滴伏立康唑粉针200 mg,Q12h。治疗3 d后,出现肝损害;后改为伏立康唑片口服100 mg,Q12h,序贯抗真菌,并加用异甘草酸镁注射液150 mg、Qd及复合辅酶粉针等降酶保肝治疗。7 d后,因药物引起肝损害进行性加重,停用伏立康唑;但肝损害继续恶化,致多脏器功能衰竭。
A 81 years old male patient with pulmonary filamentous fungal infections, treated with voriconazole injection 200 mg, Q12 h, liver damage occurred after 3 days voriconazole injection used. Hence, voriconazole injection was replaced with voriconazole pills, and treated with Magnesum Isoglycyrrhizinate injection, Coenzyme Complex injection for improving liver function. Unfortunately, the patient liver damage worsened seriously companied multiple organs dysfunction after 7 days the drug used.
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
2013年第10期795-796,共2页
The Chinese Journal of Clinical Pharmacology
关键词
伏立康唑
药物不良反应
肝损害
voriconazole
adverse drugs reaction
liver damage
