厦门市海沧地区大肠癌筛查结果分析

Screening results analysis of colorectal cancer in Haicang district of Xiamen city

目的 探讨粪便隐血试验及结肠镜检查作为大肠癌筛查主要方式的临床价值.方法 2008年12月至2010年10月,结合问卷调查和粪便隐血试验,对海沧周边农村地区4个行政村40～74岁常住居民进行初筛,高危人群接受全结肠镜检查,对检查结果进行分析.结果 总调查人数6 380例,高危人群共1 035例,1次以上粪便隐血试验阳性者580例,阳性率为9.09%.全结肠镜检查共839例,其中检出结肠癌14例,201例发现了息肉,包括腺瘤64例、非腺瘤性息肉137例,并发高级别上皮内瘤变8例.结论 结合粪隐血、问卷调查及结肠镜检查适合社区、广大农村地区患者大肠癌的筛查,有利于大肠癌及癌前病变的早期诊断及早期治疗.

Objective To explore the clinical value of fecal occult blood test（FOBT） and colonscopy in screening of colorectal cancer. Methods Preliminary screening was carried out to the inhabitants arrange from 40 to 74 years old of 4 adminis- trative villages in Haicang district combining questionaire and FOBT from December 2008 to October 2010. Colonscopy were per- formed among high risk people and the inspection results were analyzed. Results A total of 6 380 people were investigated, and 1 035 cases of which were in high-risk group. 508 cases were with more than one time positive FOBT accounting for 9.09%. Colonscopy were performed to 839 cases, and colorectal cancer was found in 14 cases ; colonic polyps were found in 201 cases, including 64 cases of adenomatous polyps and 137 cases of atypical adenomatous polyps;8 cases were with concurrent high-grade i ntraepithelial neoplasia. Conclusion Combination of FOBT, questionaire and colonoscopy was suitable for the screening of colorcctal cancer in the community and rural areas ,which is beneficial to earlier detect and treat colorectal cancer.