俘获再俘获法在制药行业职工白细胞降低者总估校正现患率的应用及探讨

Capture and recapture method in detennination of ACPR of WBC lowering staff in pharmaceutical industry.

选择本市某制药厂工人连续两年健康监护资料,应用俘获再俘获法,计算其外周血白细胞降低者的总估校正现患率(ACPR)。结果:接触组为45.27％(32.40％～57.99％),对照组为21.78％(5.44％～37.62％),两组有非常显著性差异(P<0.01),相对危险度为1.94。用常规法计算两年检出率分别为接触组16.08％,20.14％,对照组7.20％,11.67％,虽在ACPR95％可信限内,但低于ACPR值。制药行业职工白细胞降低者ACPR高于苯作业者,两组有显著性差异(P<0.05)。ACPR计算方法简便,结果准确,可用于健康监护资料的统计分析。

Capture and recapture method was used to determine ACPR of WBC lowering staff, according to the continuous two - year health monitoring data of staff in a pharmaceutical factory in the city. Result: contact group is 45.27 % (32.40 % - 57. 99 % ), contrast group is 21.78 % (5 .44 % - 37.62 % ). There is great difference between these two groups (P < o. ol), and relative danger is 1.94. Detection rate determined with routine methods: contact group is 16.08% , 20.14% , contrast group is7.20% , 11.67% . The result is lower than ACPR value, though within ACPR 95% confidence limit. ACPR value of WBC lowering staff in pharmaceutical industry is lower than that of workers exposed to benzene, and there is great difference between these two groups (P<0.05). ACPR method is simple, the result is accurate, and it can be used in analyzing statistical data of health monitoring.