3Minamino T, Kitakaze M, Papst PJ, et al. Inhibition of nitric oxide synthe- sis induces coronary vascular remodeling and cardiac hypertrophy associated with the activation of p70 S6 kinase in rats[ J]. Cardiovasc Drugs T- her,2000 ; 14 ( 5 ) :533-42.
4Baba HA, Stypmann J, Grabellus F, et al. Dynamic regulation of MEK/ Erks and Akt/GSK-3beta in human end-stage heart failure after left ventricular mechanical support:myocardial mechanotransduction-sensitivity as a possible molecular mechanism[ J ]. Cardiovasc Res ,2003 ;59 (2) :390-9.
5Parker TG, Packer SE, Schneider MD. Peptide growth factors can provoke “ fetal” contractile protein gene expression in rat cardiac myocytes [ J ]. J Clin Invest, 1990 ;85 ( 2 ) :507-14.
6Li RK, Li G, Mickle DA,et al. Overexpression of transforming growth factor-β1 and insulin-like growth factor-1 in patients with idiopathic hypertrophic cardiomyopathy[ J ]. Circulation, 1997 ;96 ( 3 ) : 874-81.
7Schultz JJ, Witt SA, Glasscock BJ,et al. TGF-β1 mediates the hypertrophic cardiomyocyte growth induced by angiotension Ⅱ[J]. J Clin Invest, 2002 ; 109 (6) :787-96.
