他汀类药物治疗急性脑梗死作用机制的研究进展

Research progress on action mechanism of statins in the treatment of acute cerebral infarction

急性脑梗死是指由于脑部血液供应障碍,缺血、缺氧引起的局限性脑组织缺血性坏死或脑软化,在我国中老年人中的发病率、病死率、致残率、并发症发生率及复发率均非常高。他汀类药物可用于治疗和预防缺血性脑卒中,该文就其作用机制研究进展作一综述。

Acute cerebral infarction refers to local ischemic necrosis or softening of the brain tissue caused by the blood supply disturbance,ischemia,hypoxia.Its morbidity,mortality,and the incidence of complications and recurrence rates in the elderly are very high in China.Statins can be used for the treatment and prevention of acute cerebral infarction.This paper reviewed the research progress on its action mechanism.