摘要
miRNA作为一类内源性的,小型非编码RNA,通过其种子序列与靶基因互作,以序列特异性方式调控靶基因的表达,参与多种生理、生化和病理的过程。本文综述了近年来miRNA在山羊泌乳生理、肌肉生长和发育、毛囊皮肤发育和繁殖生理等方面的研究,为相关研究提供参考。
MicroRNA (miRNA) is a class of non-coding small RNA,which regulates the expression of message RNA specifically.miRNA plays crucial roles during a variety of physiological,biochemical and pathological processes of organisms,by means of post-transcriptional regulation.In this article,the recent studies of miRNAs in caprine lactation physiology,muscle growth and development,hair follicles and skin development,and reproduction physiology were reviewed,so as to offer useful suggestions for miRNAs research in goat.
出处
《家畜生态学报》
北大核心
2013年第8期6-10,20,共6页
Journal of Domestic Animal Ecology
基金
高等学校博士学科点专项科研基金项目(20120204110007)
国家自然基金面上项目(No.31172184)
关键词
山羊
MIRNA
泌乳生理
肌肉生长和发育
毛囊发育
繁殖生理
goat
miRNA
lactation physiology
muscle growth and development
hair follicles and skin development
reproduction physiology