N-甲基甲磺酰胺的合成研究

Synthesis of N-Methyl Methanesulfonamide

以1，2-二氯乙烷为溶剂，甲基磺酰氯和一甲胺气体反应，控制反应温度20～30℃，反应结束后，抽真空2h，10～15℃过滤，最后蒸馏二氯乙烷到残余溶剂检测合格，得到N-甲基甲磺酰胺成品，收率大于93％，含量大于99％。

Synthesis of N - methyl methanesulfonamide was achieved by reacting methanesulfonyl chloride and gas methylamine in 1,2 - dichloroethane as solvent and controlling temperature between 20 - 30℃. Gas bleeding was executed after reaction completed, then the reaction suspension was filtered. 1,2 -dichloroethane was recycled by distilling filtrate under vacuum. N - methyl methanesulfonamide was received by high vacuum. The yield of the destination product was more than 93%, and the purity was more than 99%.