剥夺睡眠脑电图与动态脑电图对青少年癫痫诊断的对比研究

The Comparative Study of Sleep-Deprivation Electroencephalogram(SDEEG) and Ambulatory Electroencephalogram(AEEG) in the Diagnosis of Epilepsy for Adolescents

目的对比分析剥夺睡眠脑电图与动态脑电图对青少年癫痫诊断的临床应用价值。方法对239例7～18岁临床拟诊癫痫患者分别进行剥夺睡眠(107例)与动态(132例)脑电图检查,并对两组检查结果进行比较分析。结果 1)剥夺睡眠脑电图总体阳性率及痫样放电检出率均低于动态脑电图;2)剥夺睡眠脑电图对于年龄15岁以下的青少年痫样放电有较高阳性率,而动态脑电图检查各年龄段阳性率相对均衡;3)青少年癫痫患者痫样放电多出现在睡眠期,尤其是非快速眼动期Ⅰ～Ⅱ期,而剥夺睡眠脑电图睡眠期的痫样放电检出率高于动态脑电图。结论剥夺睡眠脑电图或动态脑电图检查可以提高青少年癫痫诊断阳性率,动态脑电图适合各年龄段青少年,而剥夺睡眠脑电图适合15岁以下的青少年,尤其是睡眠期易发病的患者。

Objective To investigate the clinical value of SDEEG and AEEG in the diagnosis of epilepsy for adolescents. Methods 239 cases of 7-18 years old patients who diagnosed as epilepsy were detected by SDEEG （107 cases） and AEEG （132 cases） sepa- rately, then we did a comparative analysis. Results t. The overall positive rate and epileptiform discharge detection rate of SDEEG were lower than which of AEEG. 2. SDEEG had a higher epileptiform discharge detection rate among the patients under 15, while AEEG had a relative equilibrium positive rate in all age groups. 3. Adolescent＂ patients＇ epileptifonn discharge were usually occurred in sleep stage especially in none rapid eye movement I-II period. Epileptiform discharge detection rate of SDEEG was higher than which of AEEG in sleep stage. Conclusions SDEEG and AEEG can enhance the positive diagnostic rate of epilepsy. AEEG is suit- able for all age groups, and SDEEG is suitable for patients under 15 years old, especially for those who tends to take attack in sleep stage.