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连续性肾脏替代治疗中的抗凝方法研究 被引量：5

Progress of anticoagulation for continuous renal replacement therapy
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摘要 管路凝血常发生在连续性肾脏替代治疗(CRRT)期间,一般需使用抗凝药物。普通肝素是目前最常用的抗凝药物,但其有增加出血风险和发生肝素诱导血小板减少症的可能。新的抗凝方法各具优缺点。本文综述目前CRRT中使用的抗凝药物及抗凝方法。 Circuit clotting occurred in continuous renal replacement therapy （CRRT） usually needs to be treated with anticoagulation. Heparins are the most commonly used for CRRT. However, the disadvantages include risks of hemorrhage and heparin-induced thrombocytopenia. Each of alternative methods of anticoagulation has unique advantages and disadvantages. This review describes the progress of anticoagulation for CRRT.
作者 毕智敏 余毅
机构地区 南京军区福州总医院血液净化科
出处 《世界临床药物》 CAS 2013年第10期581-584,共4页 World Clinical Drug
关键词 连续性肾脏替代治疗 抗凝 肝素 continuous renal replacement therapy anticoagulation heparins
分类号 R459.5 [医药卫生—治疗学] R973.2 [医药卫生—药品]
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参考文献22

  • 1季大玺,龚德华,徐斌.连续性血液净化在重症监护病房中的应用[J].中华医学杂志,2002,82(18):1292-1294. 被引量：126
  • 2Ostermann M,Dickie H,Tovey L,et al.Heparin algorithm for anticoagulation during continuous renal replacement therapy[J].Crit Care,2010,14 (3):419.
  • 3Sagedal S,Hartmann A.Low molecular weight heparins as thromboprophylaxis in patients undergoing hemodialysis/hemofiltration or continuous renal replacement therapies[J].Eur J Med Res,2004,9 (3):125-130.
  • 4Joannidis M,Kountchev J,Rauchenzauner M,et al.Enoxaparin vs.unfractionated heparin for anticoagulation during continuous veno-venous hemofiltration:a randomized controlled crossover study[J].Intensive Care Med,2007,33 (9):1571-1579.
  • 5Oudemans-van Straaten HM,van Schilfgaarde M,Molenaar PJ,et al.Hemostasis during low molecular weight heparin anticoagulation for continuous venovenous hemofiltration:a randomized cross-over trial comparing two hemofiltration rates[J].Crit Care,2009,13 (6):R193.
  • 6Park JS,Kim GH,Kang CM,et al.Regional anticoagulation with citrate is superior to systemic anticoagulation with heparin in critically ill patients undergoing continuous venovenous hemodiafiltration[J].Korean J Intern Med,2011,26(1):68-75.
  • 7Kramer L,Bauer E,J oukhadar C,et al.Citrate pharmacokinetics and metabolism in cirrhotic and noncirrhotic critically ill patients[J].Crit Care Med,2003,31 (10):2450-2455.
  • 8Saner FH,Treckmann JW,Geis A,et al.Efficacy and safety of regional citrate anticoagulation in liver transplant patients requiring post-operative renal replacement therapy[J].Nephrol Dial Transplant,2012,27 (4):1651-1657.
  • 9Durao MS,Monte JC,Batista MC,et al.The use of regional citrate anticoagulation for continuous venovenous hemodiafiltration in acute kidney injury[J].Crit Care Med,2008,36(11):3024-3029.
  • 10Cubattoli L,Teruzzi M,Cormio M,et al.Citrate anticoagulation during CVVH in high risk bleeding patients[J].Int J Artif Organs,2007,30 (3):244-252.

共引文献125

同被引文献46

  • 1鄢建军,耿哲,杜翔.局部枸橼酸抗凝在高危出血倾向患者血液透析中的应用[J].护理学杂志（综合版）,2005,20(4):17-19. 被引量：8
  • 2李义莲.如何预防和护理婴幼儿腹部手术后切口裂开[J].中原医刊,2005,32(17):82-82. 被引量：1
  • 3孙秀静,王丹华,徐焱,张乐嘉,董梅.早产儿早期营养支持策略的临床研究[J].临床儿科杂志,2006,24(8):655-658. 被引量：18
  • 4Uchino S, Bellomo R, Morimatsu H, et al. Continuous renal replacement therapy:a worldwide practice survey. The beginning and ending supportive therapy for the kidney (B. E. S. T. kidney) investigators[J]. Intensive Care Med, 2007,33(9):1563-1570.
  • 5Oudemans-van Straaten h:, Fiaccadori E, Baldwin I. An- ticoagulation for renal replacement therapy: different methods to improve safety[J]. Contrib NepHrol, 2010,165 (1):251-262.
  • 6Oudemans-van Straaten HM, Kellum JA, Bellomo R. Clini cal review: anticoagulation for continuous renal re- placement therapy- heparin or citrate[J]? Crit Care, 2011,15(1):202-211.
  • 7Swartz RD, Port FK. Preventing hemorrhage in high-risk hemodialysis: regional versus low- dose heparin[J].Kid- ney Int, 1979,16(4):513-518.
  • 8Tolwani AJ, Wille KM. Anticoagulation for continuous re- nal replacement therapy[J]. Semin Dial, 2009, 22(2): 141- 145.
  • 9Oudemans-Van Straaten HM, Van Schilfgaared M, Molenaar PJ, et al. Hemostasis during low molecular weight hepa- tin anticoagulation for continuous venovenous hemofil- tration: a randomized cross- over trial comparing two hemofiltration rates[J]. Crit Care,2009,13(6):193.
  • 10Kidney disease: Improving Global Outcomes Acute Kidney Injury Workgroup. KDIGO clinical practice guidelines for acute kidney injury[J]. Kidney Int,2012,2(Suppl):l- 138.

引证文献5

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世界临床药物
2013年 第10期

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