山矾科山矾属植物化学成分及药理活性研究概况

Advances in Study on Chemical Constituents and Pharmacyological Activities in Plants of Genus Symplocos

山矾属植物分布广泛,该属中多种植物具有多种传统药用价值,主要用于治疗麻风病,妇科疾病,溃疡,疟疾,肾炎,蛇咬伤等多种疾病。山矾属植物含有黄酮类、酚类、木脂素、三萜及其皂苷等多种类型植物化学成分,具有抗肿瘤,降血糖,调血脂,抗菌,抗HIV及抑制磷酸二酯酶(PDEs)等多种药理活性。本文较系统的综述山矾属植物化学成分及药理活性研究进展,以期为更好的开发利用该属植物药用资源提供参考。

The genus Symplocos is widespread all over the world,and many species of this genus have been used as traditional herbal medicines for various ailments like leprosy,gynecological disorders,ulcers,malaria,nephritis,snake bite,etc.The genus Symplocos mainly contain terpenoids,flavonoids,phenols,lignans,which had been proved to have diverse biological activities,particularly anti-HIV activity,inhibitory activities against phosphodiesterase,hypolipidemic activity,antidiabetic effect and antitumor applications.In this review article,we will summarize the chemical and pharmacological studies on the Genus Symplocos to provide a reference for future research and development of the genus.