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急性冠脉综合征行PCI术患者中替罗非班的应用分析 被引量:2

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摘要 目的探讨替罗非班对行PCI术的急性冠脉综合征(ACS)患者的应用效果。方法选取我院2011年1月。2013年7月间行PCI术的ACS患者62例,随机分为对照组和治疗组,治疗组术中应用盐酸替罗非班注射液。结果治疗组患者术中无复流发生率低于对照组,术后出血发生率明显高于对照组(P〉0.05),住院期间不良心脏事件发生率和半年后再住院率、心血管事件发生率均显著低于对照组(P〈0.05)。结论ACS行PCI术患者应用替罗非班可有效地减少术后不良心脏事件发生率,但术后出血率较高,须注意药物使用禁忌。
作者 张孟浪
出处 《心血管病防治知识(学术版)》 2013年第10期47-48,共2页 Prevention and Treatment of Cardiovascular Disease
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  • 1陈灏珠.心脏病学[M].北京:人民卫生出版社,2007:1557-1558.
  • 2SHAMIR R M,SALIM Y,MICHEL E B,et al.Effect of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention:the PCI-cure study[J].Lancet,2001,358:527-533.
  • 3MARC S,CHRISTOPHER P C,MICHAEL G,et al.Effect of clopidogrel pretreatment before percutaneous coronary intervention in patients with ST-elevation myocardial infarction treated with fibrinolytics:the PCI-CLARITY study[J].JAMA,2005,294:1224-1232.
  • 4GURBEL P A,ANTONINO M J,BLIDEN K P,et al.Platelet reactivity to adenosine diphosphate and long-term ischemic event occurrence following percutaneous coronary intervention:a potential antiplatelet therapeutic target[J].Platelets,2008,19:595-604.
  • 5DEPTA J P,BHATT D L.Aspirin and platelet adenosine diphosphate receptor antagonists in acute coronary syndromes and percutaneous coronary intervention:role in therapy and strategies to overcome resistance[J].Am J Cardiovasc Drugs,2008,8:91-112.
  • 6GURBEL P A,BLIDEN K P,HIATT B L,et al.Clo-pidogrel for coronary stenting:response variability,drug resistance,and the effect of pretreatment platelet reactivity[J].Circulation,2003,107:2908-2913.
  • 7LONGSTRETH K L,WERTZ J R.High-dose clopidogrel loading in percutaneous coronary intervention[J].Ann Pharmacother,2005,39:918-922.
  • 8PATTI G,COLONNA G,PASCERI V,et al.Randomized trial of high loading dose of clopidogrel for reduction of periprocedural myocardial infarction in patients undergoing coronary intervention:results from the ARMYDA-2 (antiplatelet therapy for reduction of myocardial damage during angioplasty) study[J].Circulation,2005,111:2099-2106.
  • 9SMITH S C Jr,FELDMAN T E,HIRSHFELD J W J,et al.ACC/AHA/SCA I 2005 guideline update for percutaneous coronary intervention-summary article:a report of the American college of cardiology/American heart association task force on practice guidelines(ACC/AHA/SCA I writing committee to update the 2001 guidelines for percutaneous coronary intervention)[J].Circulation,2006,113:156-175.
  • 10STEINHUBL S R,BERGER P B,MANN J T,et al.Early and sustained dual oral antiplatet therapy following percutaneous coronary intervention:a randomized controlled trial[J].JAMA,2002,288:2411-2420.

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