一点红地上部分的化学成分研究(Ⅱ)

Chemical Constituents of the Aerial Parts of Emilia sonchifolia(Ⅱ)

目的研究一点红地上部分的化学成分。方法采用硅胶、MCI、ODS、Sephadex LH-20及RP-HPLC等多种色谱技术对一点红地上部分的化学成分进行分离纯化,根据理化性质和波谱数据分析鉴定化合物的结构。结果从一点红地上部分的醇提物分离得到18个化合物,分别鉴定为异鼠李素-3-O-α-L-鼠李糖苷(1),阿福豆苷(2),槲皮素-7-O-α-L-鼠李糖苷(3),5,2',6'-trihydroxy-7-methoxyflavone 2'-O-β-D-glucopyranoside(4),槲皮素-3-O-α-L-鼠李糖苷(5),香叶木苷(6),异鼠李素-3-O-芸香糖苷(7),蒙花苷(8),牡荆素(9),槲皮素-7-O-β-D-葡萄糖苷(10),芹菜素-6,8-二-C-β-D-葡萄糖苷(11),对羟基苯乙酸甲酯(12),3,4-二羟基-苯乙酸(13),短叶苏木酚(14),绿原酸(15),绿原酸甲酯(16),掌叶半夏碱戊(17),尿苷(18)。结论除化合物5,11外,其余均为首次从该属植物中分离得到。

OBJECTIVE To study the chemical constituents of the aerial parts of Emilia sonchifolia. METHODS The chemical constituents were isolated and purified by chromatographies on silica gel, MCI gel, ODS, and Sephadex LH -20 columns, as well as RP-HPLC. And their structures were identified on the basis of physicochemical properties and spectral data. RESULTS Eighteen compounds were obtained from the aerial parts of E. sonchifolia and identified as isorhamnetin-3-O-a-L-rhamnopyranoside （ 1 ） , afzelin （2）, quercetin-7-O-a-L-rhamnopyranoside（3）, 5,2＇,6＇-trihydroxy-7-methoxyflavone 2＇-O-/3-D-glucopyranoside（4） , quercetin-3-O- a-L-rhamnopyranoside（5）, diosmin（6）, isorhamnetin-3-O-rutinoside（7）, linarin（8）, vitexin（9）, quercetin-7-O-β-D-glucopyrano- side （ 10 ） , vicenin-2 （ 11 ）, methyl 4-hydroxybenzeneacetate （ 12 ）, 3,4-dihydroxybenzeneacetic acid （ 13 ） , brevifolin （ 14 ） , chlorogenic acid（ 15）, methyl chlorogenate（16）, pedatisectine E（17）, and uridine（18）, respectively. CONCLUSION All compounds are i- solated from this genus for the first time except compounds 5 and 11.