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泛素-蛋白酶体通路及其与胆道疾病相关性研究进展

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摘要 泛素-蛋白酶体通路(UPP)是真核生物细胞质和细胞核内依赖于ATP、非溶酶体途径的蛋白质降解通路。UPP通路不仅能降解变性、异常或起短暂作用的蛋白质,而且能降解植物色素、转录因子、内膜蛋白和细胞周期蛋白等天然蛋白质,因而在转录水平调节、蛋白质降解、蛋白质稳定状态调节、程序性细胞死亡、
出处 《浙江医学》 CAS 2013年第19期1780-1783,共4页 Zhejiang Medical Journal
基金 浙江省公益性技术应用研究计划项目(2011C33023)
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