摘要
评述了近几年来酶催化过渡态理论在药物 ,包括杀虫剂、杀菌剂和解毒剂 ,合理分子设计中的应用进展。参考文献 2 9篇。
The recent development and application of the transition state theory of enzyme catalyzed reactions in the rational design of drugs and agrochemicals was reviewed with 29 references.
出处
《合成化学》
CAS
CSCD
2000年第6期479-485,共7页
Chinese Journal of Synthetic Chemistry
关键词
酶抑制剂
药物
分子设计
酶催化过渡态理论
Enzyme, Transition state analogue, Inhibitor, Rational design, Drugs, Agrochemicals, Catalysp