婴儿脑积水合并感染的危险因素分析

Infant hydrocephalus clinical analysis of infectious agents

目的 通过回顾性分析96例月龄12个月以下的脑积水患儿手术前感染相关因素,应用统计学方法探讨婴儿脑积水感染的危险因素. 方法 对本院2007年2月至2010年7月收治的96例月龄12个月以下的脑积水患儿（设为全组）术前病史及相关检查结果进行分析.并将月龄小于3个月的患儿（设为小龄组）与月龄3～12个月的患儿（设为大龄组）分组进行比较分析.应用SPSS 13.0统计软件,对定量资料采用配对t检验方法,对于定性资料采用x2检验,分析脑积水患儿颅内感染的危险因素,并比较不同年龄组患儿感染因素的差异. 结果 大龄组脑积水患儿颅内感染率为7％,小龄组脑积水患儿颅内感染率为33％,较大龄组明显增高.术前有颅内出血史不增加脑积水感染的机率.术前短期应用抗生素不降低脑积水感染的发生率.在小龄组中,曾有感染病史或新生儿期病理性黄疸病史的患儿,发生脑积水感染的机会增多. 结论 年龄越小,脑积水感染的几率越高.在小龄组中,曾有感染史或新生儿病理性黄疸史的脑积水患儿应特别警惕脑积水感染的可能,需行脑脊液检查.大龄组脑积水患儿中,为排除颅内感染,术前也应行脑脊液检查.

Objetive We retrospective analysis of 96 cases through age 12 months or less in infant with hydrocephalus related factors,the application of statistical methods to investigate infant hydrocephalus risk factors for infection.Methods Our hospital from February 2007 to July 2010 were treated 96 cases of age 12 months following the hydrocephalus in children （as a full group） preoperative history and related test results were analyzed.And less than 3 months of age infants （set to a small age group） with age from 3 to 12 months in children （Make older group） groups were compared.Application of SPSS 13.0 statistical software for quantitative data using a paired t-test,using the x2 test for qualitative data analysis in children with hydrocephalus,intracranial infection risk factors in children of different age groups and compare the differences infection factors.Results Older children group with hydrocephalus,intracranial infection was 7％,small age group of children with hydrocephalus intracranial infection rate was 33％.It was significantly higher than the Older children group.Preoperative history of intracranial hemorrhagewith hydrocephalus does not increase the chance of infection.Short-term use of antibiotics before surgery does not reduce the incidence of infection with hydrocephalus.In small age group,had a history of infection or a history of neonatal jaundice in children with hydrocephalus occurs the chance of infection is higher.Conclusion The younger,the higher the chance of infection hydrocephalus.Small age group,had history of infection or a history of neonatal jaundice in children with hydrocephalus hydrocephalus should be particularly wary of the possibility of infection,the need cerebr-ospinal fluid examination.Older children with hydrocephalus group,to exclude intracranial infection,cerebrospinal fluid before surgery should also be checked.