高频彩色多普勒超声对3个月以内婴儿胆道闭锁的诊断价值

The Value of High-Frequency Color Doppler Ultrasound in the Diagnosis of Biliary Atresia in Infants Less Than 3 Months

目的 探讨经腹高频彩色多普勒超声对3个月以内的婴儿胆道闭锁的诊断价值. 方法 回顾经手术确诊为胆道闭锁患儿的超声特征,总结各声像特征对胆道闭锁诊断的敏感性、特异性、阳性预测值（positive predictive va1ue,PPV）及阴性预测值（negative predictive value,NPV）. 结果 “三角索带征”对胆道闭锁诊断的敏感性、特异性、PPV及NPV分别为48.8％、99.6％、95.2％、91.8％.胆囊形态学异常的敏感性、特异性、PPV及NPV分别为85.4％、88.6％、56.4％、97.2％.胆囊收缩功能不良的敏感性、特异性、PPV及NPV分别为87.8％、89.4％、59％、97.7％.肝包膜下血流阳性对胆道闭锁诊断的敏感性、特异性、PPV及NPV分别为73.2％、92.4％、62.5％、95.2％. 结论 经腹高频彩色多普勒超声可较准确地从胆汁淤积性肝病患儿中筛查出胆道闭锁患儿.

Objetive To assess the value in the diagnosis of biliary atresia in infants less than 3months.Methods Retrospective analysis of their performance of sonography who were diagnosed with biliary atresia based on surgery,The sensitivity,specificity,positive predictive value （PPV）,and negative predictive value （NPV） were calculated for each sonographyvariable in isolation.Results The triangular cord sign had a sensitivity,specificity,PPV,and NPV of 48.8％,99.6％,95.2％,and 91.8％,respectively.The sensitivity,specificity,PPV,and NPV of an abnormal gallbladder were 85.4％ ％,88.6％,56.4％,and 97.2％,respectively,and for non-contraction of the gallbladder were 87.8％,89.4％,59％,and 97.7％,respectively.Positive hepatic subcapsular flow had a sensitivity,specificity,PPV,and NPV of 73.2％,92.4％,62.5％,and 95.2％,respectively.Conclusion Transabdominal high-frequency color Doppler ultrasound can accurately select the infant with biliary atresia from cholestatic liver disease.