摘要
在卵类粘蛋白柱上 ,考察了酮洛芬对映体在 3种流动相体系下的保留行为 ,建立了同时分离酮洛芬及其甲酯两对对映体的较佳色谱条件。方法可用于酶法立体选择性水解或酯化过程中生成的
The enantiomeric separation of ketoprofen in three mobile phase systems on an ovomucoid (OVM) chiral stationary phase (CSP) column was investigated Suitable chromatographic conditions for simultaneous separation of the two pairs of enantiomers of ketoprofen and its methyl ester were adopted All of the four compounds occuring in the process of enzymatic stereoselective hydrolysis or esterification can be simultaneously separated.
出处
《色谱》
CAS
CSCD
北大核心
2000年第6期536-538,共3页
Chinese Journal of Chromatography
关键词
酮洛芬甲酯
手性拆分
卵类粘蛋白柱
HPLC
high performance liquid chromatography
ovomucoid
ketoprofen and its methyl ester
chiral separation
