2型糖尿病与骨质疏松症的相关性研究

Type 2 diabetes and osteoporosis correlation studies

目的：探讨2型糖尿病与骨质疏松症的相关性研究的临床观察意义。方法：选自2010年1月～2012年6月在我科住院的54倒2型糖尿病患者进行骨密度测定及糖化血红蛋白检测，并根据1年内数次糖化血红蛋白的平均值，分为控制较好组（糖化血红蛋白≤6％）和控制较差组（糖化血红蛋白〉6％），结合病程等相关因素进行分析。结果：54例2型糖尿病患者骨密度降低39例（72．2％），其中女性患病率为86．4％。1年内糖化血红蛋白平均高于正常水平，骨密度降低者血糖水平更高，两组有显著差异（P〈0．01）。结论：2型糖尿病发生骨质疏松的患病率明显高于正常人群，以女性显著，病程在9年以上者明显。骨密度降低与糖化血红蛋白水平过高密切相关。

Objective：To study the relationship of type 2 diabetes and osteoporosis,and clinical significance. Methods：54 cases of patients with type 2 dia betes on bone mineral density measurement and detection of glycosylated hemoglobin and glycosylated hemoglobin several times within 1 year based on the av-erage, divided into good control group6%or less（glycated hemoglobin）control and poor groups（glyeated hemoglobin stl3 of 6%）, combined with the course of the disease and related factors were analyzed. Results：54 cases of type 2diabetes patients,39 cases（72.2%）of the loss of female prevalence was86.4%. Glyco-sylated hemoglobin within 1 year, on average, higher than normal levels, bone mineral density decreased blood glucose levels, higher in the two groups had sig＋nificant difference（P〈0.01）. Conclusion：type 2 diabetes significantly higher than that of normal popuiation,the prevalence of osteoporosis in women signifi-cantly, the course of the disease in more thangyears is obvious. Bone mineral density lower and high glyeosylated hemoglobin levels are closely related.