妇产科医院感染特点及病原菌耐药性研究

CHARACTERISTICS OF HOSPITAL INFECTION AND DRUG RESISTANCE OF PATHOGENIC BACTERIA IN OBSTETRICS AND GYNECOLOGY DEPARTMENT

目的研究医院妇产科医院感染特点及病原菌耐药情况,为临床合理使用抗菌药物提供科学依据。方法采用前瞻性监测与回顾性调查相结合的方法,对2011年某医院妇产科3 063例住院患者的临床资料进行了调查。结果该医院妇产科在2011年度住院患者医院感染率为3.07%,例次感染率3.33%。从医院感染患者送检标本中共分离出病原菌59株,革兰阴性菌占45.8%,革兰阳性球菌占30.5%。所分离的临床感染病原菌对多种抗菌药物存在较高的耐药率。结论妇产科住院患者医院感染发病率低于平均水平,感染病原菌中革兰阴性杆菌比例稍高于革兰阳性球菌,但普遍耐药。

Objective To study the characteristics of hospital infection and drug resistance of pathogenic bacteria in obstetrics and gynecology department in a comprehensive hospital, and to provide scientific basis for clinical rational use of antibacterial drugs. Methods Prospective monitoring and retrospective investigation were used to analyze the clinical data of 3 063 patients in obstetrics and gynecology department in year 2011. Results The ratio of hospital infection from obstetrics and gynecology department is 3.07% in year 2011, and the case of infection rate is 3.33%. A total of 59 pathogenic bacteria were isolated, the gram -negative bacillus accounted for 45.8% and gram -positive cocci accounted for 30. 5%. Higher drug resistance rates were observed in those pathogenic bacteria. Conclusion The ratio of hospital infection from obstetrics and gynecology department is lower than the average. The proportion of gram - negative bacillus in all pathogenic bacteria is slightly higher than that of gram - positive cocci, but the drug resistance is common.