我院住院患者抗菌药物应用分析

Application Analysis of Antibacterial Agents in Inpatients of Our Hospital

目的:分析我院住院患者抗菌药物的使用情况,为开展抗菌药物专项整治活动提供依据,促进抗菌药物的合理应用。方法:利用计算机网络系统收集2009-2011年我院院患者抗菌药物使用的数据资料,采用Excel 2003对各项数据进行汇总,计算抗菌药物的用药频度(DDDs)、累计DDDs及抗菌药物使用强度(antibacterial use density,AUD)并进行分析。结果:2009-2011年我院AUD分别为每百人天86.60,88.40,62.10限定日剂量(DDD)。DDDs排序前10位的抗菌药物中,头孢菌素占主体地位,且限制使用级抗菌药物占90%,抗菌药物限定日费用(DDC)值偏高。结论:我院抗菌药物使用存在用药过度、用药集中、抗菌药物DDC偏高等不合理问题,需进一步加强监督管理。

Objective： To analyze the application status of antibacterial agents in inpatients of our hospital so as to provide a basis for the special rectification activities for antibacterial agents and promote the reasonable use of antibac-terials . Methods： Using a computer network system to collect data of antibacterials application in inpatients of our hos-pital during 2009 - 2011 . The use frequency of antibacterials （ DDDs ） , cumulative DDDs and the antibacterial use density （ AUD ） were calculated and analyzed upon the data collection using Excell2003 . Results： During 2009 - 2011 the AUD was 86 . 60 DDD , 88 . 40 DDD and 62 . 10 DDD respectively . Cephalosporins were mostly used among the top 10 antibacterial agents in DDDs and 90% of the antibacterial drugs belonged to the class of restriction for use and the daily defined cost （ DDC ） of antibacterials was high . Conclusion： Problems existed in the application of antibacte-rial agents in our hospital such as over medication , concentrated use of drugs and high DDC . The supervision and management of antibacterials need to be further strengthened .