摘要
目的:优化加味定喘片乙醇提取工艺。方法:采用正交试验设计法,以盐酸麻黄碱、黄芩苷含量和出膏率为评价指标,优选加味定喘片乙醇提取工艺。结果:加味定喘片乙醇提取工艺优选为加60%乙醇回流提取2次,每次2 h,第1次加10倍量,第2次加8倍量。结论:优选的提取工艺科学合理,可为工业化生产提供依据。
Objective: To op timize the ethanol extraction process for jiaweidingchuan tablets . Methods: Based on the orthogonal experiment design and using the contents of ephedrine hydrochloride and baicalin and the rate of extrac-tum as indexes to op timize the ethanol extraction process for jiaweidingchuan tablets . Results: The op timum condition for the ethanol extraction of jiaweidingchuan tablets was the reflux extraction twice with addition of 60% ethanol , 2 hours each time ( 10 and 8 times in volume respectively ) . Conclusion: The op timized extraction process is scientific and reasonable , which can provide a basis for commercial productions .
出处
《中国执业药师》
CAS
2013年第11期19-22,共4页
China Licensed Pharmacist
关键词
加味定喘片
盐酸麻黄碱
黄芩苷
出膏率
正交设计
乙醇提取工艺
Jiaweidingchuan Tablets
Ephedrine Hydrochloride
Baicalin
Orthogonal Design
Rate of Extractum
Ethanol Extraction Process