期刊文献+

CD133表达分级指导直肠癌个体化放疗的研究

原文传递
导出
摘要 本研究旨在探讨将直肠癌组织CDl33表达分级应用于指导直肠癌个体化放疗的可行性,现报道如下。一、材料与方法1.材料:BALB/c雄性裸鼠30只,年龄6~8周,体质量加~24g,购自上海斯莱克实验动物有限责任公司。直肠癌组织直接来源于杭州市第三人民医院肛肠外科直肠癌手术切取的标本,经医院伦理委员会审核通过且事先取得患者的知情同意。CDl33一抗为兔抗人单克隆抗体CDl33(C2489)RabbitmAb,购自CellSignalingTechnology公司;
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2013年第11期2413-2413,共1页 Chinese Journal of Experimental Surgery
基金 国家自然科学基金资助项目(81101876/H1617) 浙江省自然科学基金资助项目(Y2110782) 浙江省科技厅公益技术研究社会发展项目(2012C33097) 浙江省医药卫生平台骨干人才项目(2011RCA035)
  • 相关文献

参考文献2

二级参考文献14

  • 1Horst D,Kriegl L,Engel J. Prognostic significance of the cancer stem cell markers CD133,CD44,and CD166 in colorcctal cancer[J].Cancer Investigation,2009,(08):844-850.
  • 2Horst D,Kriegl L,Engel J. CD133 expression is an independent prognostic marker for low survival in colorectal cancer[J].British Journal of Cancer,2008.1285-1289.
  • 3Takahashi S,Kamiyama T,Tomaru U. Frequency and pattern of the stem cell marker CD133 have strong prognostic effect on the surgical outcome of colorectal cancer patients[J].Oncology Reports,2010,(05):1201-1212.
  • 4Zhao P,Li Y,Lu Y. Aberrant expression of CD133 protein correlates with Ki-67 expression and is a prognostic marker in gastric adenocarcinoma[J].BMC Cancer,2010.218-224.doi:10.1186/1471-2407-10-218.
  • 5Ieta K,Tanaka F,Haraguchi N. Biological and genetic characteristics of tumor-initiating cells in colon cancer[J].Annals of Surgical Oncology,2008.638-648.
  • 6Verneulen L,Todaro M,de Sousa Mello F. Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity[J].Proceedings of the National Academy of Sciences(USA),2008.13427-13432.
  • 7Laharge MA,Bissell MJ. Is CD133 a marker of metastatic colon cancer stem cells[J].Journal of Clinical Investigation,2008,(06):2021-2024.
  • 8O'Brien CA,Pollett A,Gallinger S. A human colon cancer cell capable of initiating tumor growth in immunodeficient mice[J].Nature,2007,(04):106-110.
  • 9Todaro M,Alea MP,Di Stefano AB. Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4[J].Cell Stem Ce11,2007,(04):389-402.
  • 10Dongho Choi,Hyo Won Lee,Kyung Yul Hur,Jae Joon Kim,Gyeong-Sin Park,Si-Hyong Jang,Young Soo Song,Ki-Seok Jang,Seung Sam Paik.Cancer stem cell markers CD133 and CD24 correlate with invasiveness and differentiation in colorectal adenocarcinoma[J].World Journal of Gastroenterology,2009,15(18):2258-2264. 被引量:14

共引文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部