响应面法优化Fe^(3+)助纤维素酸水解制备微晶纤维素

Hydrolysis of Cellulose for Preparation of Microcrystalline Cellulose Catalyzed by Fe^(3+) Based on Response Surface Methodology

基于Central-Composite实验设计(CCD),采用响应面法(RSM)研究了Fe3+催化纤维素酸水解制备微晶纤维素的最佳工艺条件,并考察了Fe3+浓度、HCl浓度、反应时间和温度4个因素对水解纤维素得率的影响,建立了相关的数学回归模型。实验结果表明:各因素对水解纤维素得率的影响显著性顺序为HCl浓度>温度>反应时间>Fe3+浓度;优化后水解纤维素的得率为83.18%,与模型的预测值基本相符;通过FTIR和XRD分析表明,最佳工艺条件下水解纤维素具有和纤维素相似的化学结构,结晶度较高。

The acid hydrolysis process conditions of cellulose catalyzed by Fe3＋ in the process of preparation of microcrystalline cellulose based on response surface methodology （RSM） was investigated, the technological parameters such as Fe3＋ concentration, HCl concentration, temperature and time were optimized and the related model was established. The results showed that parameters influence on the yield of hydrocellulose from significant order to HCl concentration , temperature 〉 time 〉 Fe3＋ concentration; The yield of hydrocellulose under optimized condition was 83.18%, which was well agreed with the predicted value; The FTIR and XRD analysis showed that the hydrocellulose had the same functional groups and higher crystallinity compared with cellulose.