摘要
支气管哮喘（简称哮喘）是多种炎症细胞及炎症介质参与形成的慢性炎症性的疾病，但是具体的发病机制尚不十分清楚。最近研究发现Th17细胞及其细胞因子IL-17参与哮喘的发生发展过程，并起重要的作用。Th17细胞是一类新型的CD4＋T细胞，IL-17是其主要的细胞因子。本综述主要阐述Th17、IL-17在哮喘发病机制中的作用。
Bronchial asthma （asthma） is a chronic inflammatory disease which involvding a variety of inflammatory cells and inflammatory mediators, but the specific pathogenesis is not yet clear. Recent studies have found that Th17 cells and their cytokine IL17 involved in the genesis and development of asthma, and play an important role in the process. Th17 cells is a novel class of CD4 ＋ T cells, IL-17 is the main cytokines. In this review, we mainly investigate the role of Th17/IL-17 in the pathogenesis of asthma.
出处
《国际呼吸杂志》
2013年第21期1653-1656,共4页
International Journal of Respiration
