慢性阻塞性肺疾病合并症的研究进展

Research Progress in the Complications of Chronic Obstructive Pulmonary Disease

慢性阻塞性肺疾病(COPD)不仅仅是局限于肺部的疾病,它常合并心血管疾病、糖尿病等,造成全身损害。近年来这种全身损害及合并症日益受到重视,但其产生的机制仍不清楚,目前研究认为肺部炎症溢出可能是导致全身炎性反应及产生合并症的重要原因。该文围绕COPD肺部炎症与全身炎症、合并症的关系及合并症的干预措施进行综述。

Chronic obstructive pulmonary disease（COPD） is not only confined to the lung disease, but is also often combined with cardiovascular disease, diabetes and other diseases, causing damage to the body. In recent years,its systemic damage and complications have received increasing attention, while the mechanism remains unclear,which may be associated with lung inflammation overflow leading to systemic inflammatory response com- plications. Here is to make a review of the relationship of COPD lung inflammation and systemic inflammation, and comorbidities, as well as the interventions for the complications.