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颅内动脉粥样硬化的危险因素和治疗研究进展 被引量：4

Research Progress in Risk Factors and Treatment of Intracranial Atherosclerosis
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摘要 颅内动脉粥样硬化(AS)是引起缺血性脑卒中的主要原因之一,各种外界因素、遗传因素及自身内环境的异常都与颅内AS的形成相关,其中较为重要的因素包括年龄、代谢综合征和血脂异常等。这些因素在导致颅内AS形成的过程中危险程度各有不同。在由AS引起的缺血性脑卒中的二级预防中,阿司匹林是最重要的抗血小板药物之一,但一些新的抗血小板药物在抗AS过程中的作用也值得关注。 Intracranial atherosclerotic disease（ICAD） is the most common proximate mechanism of ischemic stroke. Tbere are many risk factors associated with intracranial atherosclerosis, such as age, metabolic syndrome and dyslipidemia,whieh may cause different degrees of risks for ICAD. In terms of secondary prevention of stroke due to intracranial atherosclerotic stenosis, aspirin continues to be the preferred antiplatelet agent, while some new antiplatelet agents are also worth attention for their role of atheroselerosis resistance.
作者 所森 李国忠
机构地区 哈尔滨医科大学附属第一临床医院神经内科
出处 《医学综述》 2013年第21期3932-3934,共3页 Medical Recapitulate
关键词 动脉粥样硬化 性别 代谢综合征 血脂 药物治疗 血管内治疗 Atherosclerosis Gender Metabolic syndrome Blood tat Drug therapy Endovascu- lar therapy
分类号 R743.1 [医药卫生—神经病学与精神病学]
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  • 1秦俭（编译）,赵妍（编译）.胆固醇水平与出血性脑卒中发病的人群差别：血清胆固醇与出血性脑卒中、缺血性脑卒中及心肌梗死：韩国国家卫生系统前瞻性队列研究[J].世界急危重病医学杂志,2006,3(4):1397-1400. 被引量：43
  • 2Sacco RL, Adams R, Albers G, et al; American Heart Association; American Stroke Association Council on Stroke; Council on Cardiovascular Radiology and Intervention; American Academy of Neurology.Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: co-sponsored by the Council on Cardiovascular Radiology and Intervention: the American Academy of Neurology affirms the value of this guideline. Stroke, 2006, 37:577 -617.
  • 3Bhatt DL, Fox KA, Hacke W, et al; CHARISMA Investigators. Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. N Engl J Med, 2006, 354:1706 - 1717.
  • 4Diener HC, Bogousslavsky J, Brass LM, et al; MATCH investigators. Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial. Lancet, 2004, 364:331 -337.
  • 5ESPRIT Study Group, Halkes PH, van Gijn J,Kappelle LJ, et al. AAspirin plus dipyridamole versus aspirin alone after cerebral ischaemia of arterial origin (ESPRIT): randomised controlled trial. Lancet, 2006, 367:1665 - 1673.
  • 6Lindgren A, Husted S, Staaf G, et al. Dipyridamole and headache: a pilot study of initial dose titration. J Neurol Sci, 2004, 223:179 - 184.
  • 7Chang YJ, Ryu SJ, Lee TH. Dose titration to reduce dipyridamolerelated headache. Cerebrovasc Dis, 2006, 22:258 -262.
  • 8Schroeder K, Fahey T, Ebrahim S. How can we improve adherence to blood pressure-lowering medication in ambulatory care? Systematic review of randomized controlled trials. Arch Intern Med, 2004, 164: 722 - 732.
  • 9Goldstein LB, Adams R, Alberts MJ, et al; American Heart Association/American Stroke Association Stroke Council; Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; Quality of Care and Outcomes Research Interdisciplinary Working Group; American Academy of Neurology. Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council. Stroke, 2006, 37:1583 -1633.
  • 10Pandey DK, Gorelick PB. Should statin agents be administered to all patients with ischemic stroke? Arch Neurol, 2005,62:23 -24.

共引文献506

同被引文献56

  • 1刘永升,魏梅,刘会英,岳媛媛,王乐,张慧敏,刘丽.西洛他唑对老年急性冠脉综合征患者血清炎性细胞因子及血脂代谢的影响[J].实用老年医学,2013,27(7):594-597. 被引量：1
  • 2徐宝华,赵慧颖.动脉粥样硬化不稳定斑块的研究进展[J].心血管病学进展,2005,26(5):498-501. 被引量：23
  • 3Liu L,Wang D,Wong K S,et al. Stroke and stroke care in China: huge burden, significant workload, and a national priority [J]. Stroke,2011,42(12):3651-3654.
  • 4Xu W H,Li M L,Gao S,et al. In vivo high-resolution MR imaging of symptomatic and asymptomatic middle cerebral artery athero-sclerotic stenosis[J]. Atherosclerosis,2010,212(2) :507-511.
  • 5Chung G H, Kwak H S, Hwang S B, et al. High resolution MR imaging in patients with symptomatic middle cerebral artery ste- nosis[J]. Eur J Radiol,2012,81(12) :4069-4074.
  • 6Qiao Y, Etesami M, Malhotra S, et al. Identification of intraplaque hemorrhage on MR angiography images:a comparison of contrast- enhanced mask and time-of-flight techniques[J]. AJNR, 2011, a2 (3) :454-459.
  • 7Huang Y,Teng Z, Sadat U, et al. The influence of computational strategy on prediction of mechanical stress in carotid atheroscle- rotic plaques & comparison of 2D structure-only, 3D structure-only, one-way and fully coupled fluid-strueture interaction analyses[J]. J Biomech,2014,47(6) :1465-1471.
  • 8Li L, Chai J T,Biasiolli L, et al. Black-blood multicontrast imaging of carotid arteries with DANTE-prepared 2D and 3D MR imaging [J]. Radiology,2014,273(2) :560-569.
  • 9Saam T, Hetterich H, Hoffmann V, et al. Meta-analysis and sys- tematic review of the predictive value of carotid plaque hemor- rhage on cerebrovascular events by magnetic resonance imaging [J]. J Am Coil Cardiol,2013,62(12) : 1081-1091.
  • 10Xu W H,Li M L,Gao S,et al. Middle cerebral artery intraplaque hemorrhage & prevalence and clinical relevance[J]. Ann Neurol 2012,71(2) :195-198.

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医学综述
2013年 第21期

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