功能性消化不良的治疗进展

Advance of Functional Dyspepsia Treatment

消化不良是用来描述"难以消化"的医学术语,指位于上腹部的一组异质性症状,包括器质性消化不良和功能性消化不良(FD)。FD患病率高,具有慢性、反复发作的特点,可显著降低患者的生活质量,也给医疗保健及社会经济带来严重负担。目前尚无治疗FD的特效方法及药物。该文以FD的致病因素及病理生理学改变为基础,重点阐述评估近年来FD治疗的方法及药物。

Dyspepsia is the medical term used to describe the sense of ＂ difficult digestion＂. The term refers to a very heterogenous group of symptoms,located in the upper abdomen,which can be divided into 2 main categories of organic and functional dyspepsia （F-D）. FD significantly affects quality of life and brings considerable cost for the health care system and socio-economy because of the high prevalence and the chronic or recurrent nature of symptoms. There is no treatment and drug with established efficacy for FD. Here is to make a review of the pathogenic factors and pathophysiology of FD,with emphasis on elaborating and assess- ing the treatments and drugs for FD in recent years.