金属氧化物催化苯酚-甲醇气相C-烷基化的研究进展

Research progress in vapor phase C-alkylation of phenol with methanol over metallic oxides

综述了金属氧化物催化体系下的苯酚-甲醇气相C-烷基化反应研究进展,比较了苯酚-甲醇气相邻位C-烷基化合成邻甲酚和2,6-二甲酚的工艺方法和催化体系,重点探讨了金属氧化物催化体系下苯酚-甲醇连续固定床气相烷基化法的研究现状。同时,对单一组分和多组分金属氧化物的不同C-烷基化反应活性进行了比较,在此基础上探讨了催化剂酸碱性质与反应性能的关系、催化剂失活原因、苯酚和甲醇气相邻位C-烷基化的反应机理等问题,并对今后更高效环保的金属氧化物催化剂的研究方向提出了展望,提出了纳米尺度催化剂和生物质催化剂等研究热点。

Recent progress in the metallic oxides catalysts for vapour phase ortho-selective C-alkylation of phenol with methanol was reviewed. Different catalysts systems as well as synthesis processes for vapor phase ortho-selective C-alkylation of phenol with methanol that yields o-cresol and 2,6-xylenol were compared,especially,the research progress in a continuous flow fixed-bed reactor over the metallic oxides catalysts was discussed. Furthermore,the activities of single component and multiple component metallic oxides catalysts toward C-alkylation of phenol were compared,and the relationship between the acidic-basic properties of the catalysts and the catalytic performance were clarified. The deactivation and the possible reaction mechanism were also discussed in detail. Finally,the difficulties and challenges of the novel environment-benign and high-efficiency catalysts were discussed,meanwhile the recent research hot points of anometer catalyst and biomass catalyst were proposed.