高血压患者性功能状况

Sexual function of hypertensive patients

目的调查高血压患者性功能状况及其影响因素。方法选取高血压患者300例(男性140例,女性160例),正常血压受试者129人(男性79人,女性50人)。采用国际勃起功能指数(IIEF)量表和国际女性性功能指数(FSFI)量表评价性功能,同时检测血清性激素水平。结果与正常血压组比较,高血压组男性受试者在勃起功能层面的得分低(20.94±6.28比23.48±3.89,P=0.001),而性欲、达到性高潮能力、性交满意度及总体满意度层面的得分差异无统计学意义。高血压组勃起功能障碍(ED)患病率高于正常血压组(29.3%比10.1%,P<0.01)。与正常血压组相比,高血压组女性受试者性欲(2.92±1.01比3.58±0.74,P<0.01)、性唤起(3.51±0.96比4.47±0.67,P<0.01)、阴道润滑(4.38±1.02比5.29±0.59,P<0.01)、疼痛层面的得分(4.86±1.10比5.50±0.61,P<0.01)及总分(23.83±4.50比27.56±3.28,P<0.01)低,性高潮及性满意度层面的得分差异无统计学意义。高血压组女性性功能障碍(FSD)患病率高于正常血压组(60.4%比26.0%,P<0.01)。收缩压升高(男性:β=0.149,P=0.006;女性:β=0.148,P=0.045)及年龄增加(男性:β=0.158,P=0.037;女性:β=0.263,P=0.001)为高血压患者ED或FSD的危险因素。结论高血压影响男性及女性患者的性功能。

Objective To investigate sexual function and related factors in hypertensive patients. Methods A total of 300 hypertensives （140 males and 160 females and 129 normotensives （79 males and 50 females） were enrolled. Sexual function was evaluated using international index of erectile function （IIEF） questionnaire or female sexual function index （FSFI） questionnaire. Results The scores of erection function were lower in male patients with hy- pertension compared with normotensive participants [ （ 20.94 ± 6.28 ） vs （ 23.48 ± 3.89 ） , P 〈 0. 001], while the scores of sexual desire, orgasm ability, sexual satisfaction and overall satisfaction showed no statistical difference. The prevalence of erectile dysfu2nction （ED） was higher in the male hypertensives than in the normotensive partici- pants （29.3 G vs 10.1 G, P〈0.01 ）. Compared with the normotensive women, the hypertensive women got lower scores of sexual desire [ （ 2.92 ± 1.01 } vs （ 3.58 ± 0.74 }, P〈 0.01 ], sexual arousal [ （ 3.51 ± 0.96 ） vs { 4.47 ± 0.67）, P〈0.01], vaginal lubrication [（4.38±1.02） vs （5.29±0.59）, P〈0.01], pain [（4.86±1.10） vs （5.50±0.61）, P〈0.01] and total score [（23.83±4.50） vs （27.56±3.28）, P〈0.01]. The differences in the scores of orgasm and satisfaction were not statistically significant. The prevalence of female sexual dysfunction （FSD） in hypertensive patients was higher than in normotensive participants （60.4% vs 26.0%, P〈0.01 ）. Sys tolic blood pressure increase（male： β=0. 149, P=0.006; female：β=0.148, P=0.045） and aging （male： β=0. 158, P=0.037; female： β= 0. 263, P=0. 001} were risk factors of ED and FSD in hypertensive patients. Conclusion Hypertension have negative influence on sexual functions of both male and female patients.