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多囊卵巢综合征与表观遗传学 被引量：1

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摘要 多囊卵巢综合征（PCOS）是育龄期妇女的生殖内分泌紊乱性疾病，6％～7％的妇女在生育年龄表现为PCOS。该综合征是年轻女性诊断为2型糖尿病的主要原因，PCOS常合并生殖、代谢、心血管、肿瘤、炎症和睡眠异常的情况，对女性的健康造成极大的危害。
作者 张多加 吴效科
机构地区 黑龙江中医药大学附属第一妇产科
出处 《中国妇幼保健》 CAS 北大核心 2013年第33期5574-5576,共3页 Maternal and Child Health Care of China
基金 黑龙江省教育厅科学技术研究项目〔12511498〕
关键词 多囊卵巢综合征 表观遗传学 内分泌紊乱性疾病 育龄期妇女 PCOS 2型糖尿病 生育年龄 睡眠异常
分类号 R711.75 [医药卫生—妇产科学]
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参考文献25

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共引文献53

同被引文献35

  • 1杨正望,尤昭玲,冯光荣,王瑛.多囊卵巢综合征动物模型的构建及中药干预机制述评[J].湖南中医学院学报,2006,26(1):56-58. 被引量：10
  • 2孙林,魏巍,关咏梅.u-PA、u-PAR和PAI-1在睾酮联合hCG致多囊卵巢大鼠中的表达与意义[J].生殖与避孕,2006,26(10):579-583. 被引量：14
  • 3邝少松,黄小琼,饶子亮,王刚,刘广南,潘竟锵.大鼠多囊卵巢综合征动物模型血脂代谢及抗氧化作用[J].中国比较医学杂志,2007,17(9):519-522. 被引量：11
  • 4Lowe P, Kovacs G, Howlett D, et al. Incidence of polycystic ovaries and polycystic ovary syndrome amongst women in Melbourne, Australia. Aust N Z J Obstet Gynaecol. 2005; 45(1):17-19.
  • 5马琳琳,吴效科.多囊卵巢综合征产科并发症及其防治[C].全国中西医结合妊娠期疾患专题学术会议论文集.2011:23-26.
  • 6Baka S, Zourla K, Kouskouni E, et al. Matrix metalloproteinases 2 and 9 and their tissue inhibitors in the follicular fluid of patients with polycystic ovaries undergoing in vitro fertilization. In Vivo. 2010;24:293-299.
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  • 8Manneras L, Cajander S, Holmang A, et al. A new rat mode exhibiting both ovarian and metabolic characteristics of polycystic ovary syndrome. Endocrinology. 2007; 148(8): 3781-3791.
  • 9Liu X, Andoh K, Mizunuma H,et al. Effects of recombinant human FSH (rhFSH), urinary purified FSH (uFSH), and hMG on small preantral follicles and tertiary follicles from normal adult and androgen-sterilized female mice. Fertil Steril. 2000; 73(2):372-380.
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中国妇幼保健
2013年 第33期

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