COPD易感真菌患者中医体质及预防策略研究

Study on Traditional Chinese Medicine Constitution Types of Patients with Acute Exacerbation of COPD with Secondary Pulmonary Fungal Infections(AECOPD) and Prevention and Treatment

目的:调查慢性阻塞性肺疾病(COPD)急性加重期继发真菌感染患者的中医体质类型,分析其相关性,进一步探讨COPD继发真菌感染预防策略,为中医药预防、治疗COPD继发真菌感染提供依据。方法:对356例COPD急性加重期病例进行系统回顾性研究,进行中医体质类型判定。结果:63例继发真菌感染,其中气虚质21例(33.33%),痰湿质15例(23.81%),阳虚质9例(14.29%),湿热质7例(11.11%),血瘀质5例(7.94%),阴虚质4例(6.35%),气郁质2例(3.17%)。结论:气虚质COPD患者脏腑功能低下,较其他体质易于继发真菌感染。

Objective：To investigate the traditional Chinese medicine （TCM） constitution types of the patients with acute exacerbation of chronic obstructive pulmonary disease （COPD） with secondary pulmonary fungal infections （AECOPD）,analyse the internal relativity,and discuss the ways and means of preventing and treating secondary pulmonary fungal infections,so as to provide basis for applying the TCM in preventing and treating secondary pulmonary fungal infections.Method：A retrospective study was performed in 365 AECOPD patients and their TCM constitution types were determined.Result：A total of 63 patients in 365 AECOPD patients were infected by secondary pulmonary fungi.Among the 63 cases,21 cases （33.33%） were qi-deficiency type;15 cases （23.81%） were phlegm-wetness type; 9 cases （14.29%） were yang-deciency type; 7 cases （11.11%） were wet-heat type; 5 cases （7.9%） were blood-stasis type; 4 cases （6.35%） were yin-deciency type; 2 cases （3.17%） were qi-depression type.Conclusion：The qi-deficiency type patients are more likely to be infected with secondary pulmonary fungi than other types＇ patients because of Zang and Fu Organ hypofunction.