Nafion修饰传感电极及其应用于测定强力霉素氢化物的研究

Nation Modified Sensitive Electrodes and Their Application in the Determination of Doxycycline Hydride

本文报道了Nafion修饰传感电极及其在分析测试中的应用。在pH0.9～2.2范围内,该电极对含质子化二甲胺基的强力霉素氢化物起响应。线性范围为10^(-2·7)～10^(-5·3)mol/L,检测下限为2.5×10^(-6)mol/L(石墨内导)及2.2×10^(-6)mol/L(玻碳内导)。用于测定生产中的中间体试样,获得了较好的回收率。

This paper describes Nafion modified sensitive electrodes and their application in analysis. The Nafion modified sensitive electrode has good response to monoprotonated doxycycline hydride at pH 0.9～2.2. The linear range of electrode response is 1.0×10^(-2·7)～1.0×10^(-5·3)mol/L. The detection limits are 2.5×10^(-6)mol/L (graphite substrate) and 2.2×10^(-6)mol/L(glassy carbon substrate). The potentiometric determination of the doxycycline hydride gave satisfactory recovery.