期刊文献+

Infertility treatment, a matter of a lovely sperm?

Infertility treatment, a matter of a lovely sperm?
下载PDF
导出
摘要 Nowadays, the efficiency of the infertil-ity treatment is relatively low. One of the cues to counteract this problem relies on the optimum selection of spermatozoa. We developed a new method (sperm selection assay (SSA)) based on the chemical attrac-tion of spermatozoa that are at the best functional state. Additionally, the SSA leads spermatozoa to complete and/or acquire the competence to fertilize the egg. These effects are equally observed either in nor-mal or subfertile semen samples. Those cap-abilities of SSA may improve the success of current infertility treatment. Nowadays, the efficiency of the infertil-ity treatment is relatively low. One of the cues to counteract this problem relies on the optimum selection of spermatozoa. We developed a new method (sperm selection assay (SSA)) based on the chemical attrac-tion of spermatozoa that are at the best functional state. Additionally, the SSA leads spermatozoa to complete and/or acquire the competence to fertilize the egg. These effects are equally observed either in nor-mal or subfertile semen samples. Those cap-abilities of SSA may improve the success of current infertility treatment.
出处 《Asian Journal of Andrology》 SCIE CAS CSCD 2013年第6期719-720,共2页 亚洲男性学杂志(英文版)
  • 相关文献

参考文献8

  • 1Nygren KG, Sullivan E, Zegers-Hochschild F, Mansour R, Ishihara 0 et al. International Committee for Monitoring Assisted Reproductive Technology (ICMART) world report: assisted reproductive technology 2003. Fertil Steri12011; 95: 72209-22.
  • 2Barroso G, Valdespin C, Vega E, Kershenovich R, Avila R et al. Developmental sperm contributions: fertilization and beyond. Fertil Sleri12009; 92: 835-48.
  • 3Barratt CL, Mansell S, Beaton C, Tardif S, Oxenham SK. Diagnostic tools inmale infertility-the question of sperm dysfunction. AsianJAndro/2011; 13: 53-8.
  • 4Eisenbach M, Giojalas LC. Sperm guidance in mammals-an unpaved road to the egg. Nat Rev Mol Cell 8io/2006; 7: 276-85.
  • 5Guidobaldi HA, Teves ME, Ufiates DR, Giojalas LC. Sperm transport and retention at the fertilization site is orchestrated by chemotaxis and oviduct movement. Reproduction 2012; 143: 587-96.
  • 6Teves ME, Barbano F, Guidobaldi HA, Sanchez R, Miska W et al. Progesterone at the picomolar range is a chemoattractant for mammalian spermatozoa. Fertil Steri12006; 86: 745-9.
  • 7Teves ME, Guidobaldi HA, Ufiates DR, Sanchez R, Miska W et al. Molecular mechanism for human sperm chemotaxis mediated by progesterone. PLoS ONE 2009; 4: e821l.
  • 8Gatica LV, Guidobaldi HA, Montesinos MM, Teves ME, Moreno AI et al. Picomolar gradients of progesterone select functional human sperm even in subfertile samples. Mol Hum Reprod; e-pub ahead of print 10 June 2013; doi:10.1093/molehr/gat037.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部