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Treatment of pituitary prolactinoma reverses unresponsiveness to PDE5 inhibitor therapy in men with ED and SHPRL

Treatment of pituitary prolactinoma reverses unresponsiveness to PDE5 inhibitor therapy in men with ED and SHPRL
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摘要 Dear Editor, Four patients with erectile dysfunction (ED) induced by pituitary prolactinoma presented to our clinic from 2007 to 2008. The patients had been misdiagnosed nearly 2 years earlier at other hospitals because severe ED was the initial symptom. None of these patients had experi-enced successful and satisfactory intercourse in approximately 2 years despite being treated with numerous medications, including the repeated administration of phosphodiesterase-5 inhibitors (PDE5is) (sildenafil 100 mg and/or tadalafil 20 mg). However, after successful treatment for pituitary prolactinoma, the response to PDE5is improved dramatically. The four cases are described in this report. Dear Editor, Four patients with erectile dysfunction (ED) induced by pituitary prolactinoma presented to our clinic from 2007 to 2008. The patients had been misdiagnosed nearly 2 years earlier at other hospitals because severe ED was the initial symptom. None of these patients had experi-enced successful and satisfactory intercourse in approximately 2 years despite being treated with numerous medications, including the repeated administration of phosphodiesterase-5 inhibitors (PDE5is) (sildenafil 100 mg and/or tadalafil 20 mg). However, after successful treatment for pituitary prolactinoma, the response to PDE5is improved dramatically. The four cases are described in this report.
机构地区 Department of Urology
出处 《Asian Journal of Andrology》 SCIE CAS CSCD 2013年第6期847-849,共3页 亚洲男性学杂志(英文版)
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  • 1Mindermann T,Wilson CB.Age-related and gender-related occur-rence of pituitary adenomas[J].Clin Endocrinol (Oxf),1994,41:359-364.
  • 2Ciccarelli A,Daly AF,Beckers A.The epidemiology of prolactinomas[J].Pituitary,2005,8:3-6.
  • 3Sauder SE,Frager M,Case GD,et al.Abnormal patterns of pulsatile luteinizing hormone secretion in women with hyperprolactinemia and amenorrhea:responses to bromocriptine[J].J Clin Endocrinol Metab,1984,59:941-948.
  • 4Sartorio A,Pizzocaro A,Liberati D,et al.Abnormal LH pulsatility in women with hyperprolactinaemic amenorrhoea normalizes af-ter bromocriptine treatment:deconvolution-based assessment[J].Clin Endocrinol,(Oxf)2000,52:703-712.
  • 5Dorrington J,Gore-Langton RE.Prolactin inhibits oestrogen syn-thesis in the ovary[J].Nature,1981,290:600 -602.
  • 6吴在德.外科学[M].(第六版).北京:人民卫生出版社,2006:735.
  • 7Ramot Y,Rapoport MJ,Hagag P,Wysonbeek AJ.A study of the clinical differences between women and men with hyperprolactinemia[J].Gynecol Endocrinol,1996,10:397-400.
  • 8Calle-Rodrigue RD,Giannini C,Scheithauer BW,et al.Prolactinomas in male and female patients:a comparative clini-copathologic study[J].Mayo Clin Proc,1998,73:1046-1052.
  • 9Gokalp HZ,Deda H,Attar A,et al.The neurosurgical management of prolactinomas[J].J Neurosurg Sci,2000,44:128-132.
  • 10Randall RV,Laws ER Jr,Ahbound CF,et al.Transsphenoidal mi-crosurgical treatment of prolactin-producing pituitary adenomas:results in 100 patients[J].Mayo Clin Ptoc,1983,58:108-121.

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