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简述疫苗安全性管理 被引量：5

A brief introduction to management of vaccine safety
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摘要 疫苗接种是保护公众健康最有效的措施之一,疫苗可有效降低传染病的发病率和死亡率。与疫苗的有效性评估不同,疫苗的安全性不能直接测定,只能通过有限的疫苗不良事件的相关情况来推断。对疫苗安全性监测的科学理论,全球关注的个案研究,以及注册前有关疫苗的临床试验安全性的相关事宜进行了简介。 Vaccination is one of the most effective measures to protect puplic health, vaccines can effectively reduce morbidity and mortality for infectious diseases. It is different from a evaluation for vaccine effectiveness, vaccine safety can not be measured directly; it can only be deduced from the related vaccine adverse events. In this review, we will outline the scientific framework for monitoring vaccine safety and will highlight recent case studies of global interest. Issues related to pre-licensure study of vaccine safety in clinical trials will be described briefly.
作者 吴浩飞 孙亨凡 孟胜利 杨晓明
机构地区 武汉生物制品研究所有限责任公司
出处 《微生物学免疫学进展》 2013年第5期69-74,共6页 Progress In Microbiology and Immunology
关键词 疫苗 安全性 不良事件 Vaccine Safety Adverse events
分类号 R186 [医药卫生—流行病学]
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参考文献17

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同被引文献43

  • 1常华,许彤.浅析接种吸附无细胞百白破疫苗儿童出现副反应的原因及护理方法[J].当代医药论丛,2014,12(10):71-72. 被引量：3
  • 2袁方.我国开展国际多中心临床试验的现状及改进措施[J].医药导报,2007,26(1):100-102. 被引量：22
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  • 4WHO. Polio this week as of 20 August 2014[EB/OL]. (2014 -08 -24) [2015 -08 - 09 ]. http://polioeradication. org/Dataandmonitor-ing/Poliothisweek. aspx.
  • 5Coelho FC,Codeco CT. Dynamic modeling of vaccinating behavior asa function of individual beliefs [ J ]. PLoS Comput Biol,2009,5(7):el000425.
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  • 10Streefland PH. Public doubts about vaccination safety and resistanceagainst vaccination[J]. Health Policy ,2001,55(3) :159 -172.

引证文献5

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微生物学免疫学进展
2013年 第5期

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