离子液体中钯催化炔与烯丙醇的交叉偶联反应

Pd-Catalyzed Cross-Coupling Reaction of Alkynes with Allylic Alcohol in Ionic Liquids

发展了一种在室温条件下，以PdBr2为催化剂，以[Bmim]Br/HBraq为溶剂，炔烃与烯丙醇进行交叉偶联反应的新方法，以中等及优良的产率（61%～93%）合成了溴代-1，4-二烯衍生物. 反应表现出较高的区域选择性和立体选择性. 催化体系可以循环使用4次，并且保持活性不变.

A Pd-catalyzed method was developed for cross-coupling reaction of a wide range of alkynes with allylic alcohol in ionic liquids. In the presence of PdBr2, [Bmim]Br and HBraq, the cross-coupling products can be obtained in moderate to good yields, and the reaction displayed high regio-and stereo-selectivities. The catalyst system could be recycled four times without loss of activity.