郑州地区108例血友病患者门诊用血情况及疗效分析

Analysis of outpatient blood-use and therapeutic effect of 108 patients with hemophilia in Zhengzhou area

目的 分析郑州地区血友病患者的临床症状,用血情况及临床疗效.方法 对我血液中心2012年9月～2013年4月就诊的108例血友病患者（血友病A88例,血友病B20例）的输血资料进行系统分析,统计患者的血型分布、年龄分布及临床症状、用血情况等.结果 门诊就诊的血友病患者大都在7～20岁,A、B、O三型患者人数基本相当,AB型患者相对较少,O型患者相对症状重、用血量偏大、就诊频率较高.就诊患者以关节、肌肉和皮下出血为主.结论 血友病患者应该加强预防教育,发现症状及时就诊,一旦延误治疗时机,替代治疗起效慢,恢复时间长.因为目前人凝血因子Ⅷ和凝血酶原复合物相对短缺,病情严重者可采用输血和输注凝血因子交替治疗,疗效较好.

Objective To analyze the clinical symptoms, outpatient blood- use and therapeutic effect of patients with hemophilia. Methods Systematically analyzed the blood transfusion information of 108 patients with hemophilia in outpatient department of Henan Red Cross Blood Centre from Sep 2012 to Apt 2013.（hemophilia A were 88,hemophilia B were 20）. Results The patients with hemophilia in outpatient department were almost from 7-20 years old,the pa- tient number of A,B,O blood type were similar,the patients with O blood type were more seriously than other type, used more blood production.The main symptoms were joints-bleeding,muscles-bleeding and subcutaneous hemorr hage. Conclusion This analysis reveals that the patients with hemophilia shold be cured in time, the symptoms should be relieved more quickly if it was cured early.