症状性颅内动脉狭窄血管内支架治疗的临床效果观察

Endovascula stent in treatment of symptomatic intracranial arterial stenosis

目的探讨血管内支架治疗症状性颅内动脉狭窄的临床效果。方法选择症状性颅内动脉狭窄的患者30例为研究对象,采用血管内支架治疗,另选择30例药物治疗的患者作为对照,分析两组治疗前后临床效果。结果研究组无死亡病例和脑出血病例,其术后狭窄程度显著小于对照组,主要终点事件、缺血性脑卒中病例少于对照组(P均<0.05)。手术后即刻和治疗后30d,狭窄程度较治疗前显著下降(P<0.01)。结论血管内支架治疗症状性颅内动脉狭窄具有较好的疗效,并且术后并发症较少,终点事件明显较少。

Objective To discuss clinical efficacy of endovascula stent in treatment of symptomatic intracranial arterial stenosis. Methods Thirty cases with symptomatic intracranial arterial stenosis were selected and were treated by en- dovascula stent. Thirty cases treated by drugs were selected as control group. Clinical efficacy was compared between two groups. Results There was no death case and hematencephalon case. Postoperative stenosis degree of study was less than control group, and cases with the primary end point events and cerebral arterial thrombosis were less than control group （P all〈0.05）. Degrees of coronary artery stenosis and 30 d after surgery of study immediate post-surgery were less than before surgery（P〈0.01 ）. Conclusion Endovascula stent in treatment of symptomatic intracranial arterial stenosis shows good clinical efficacy, with less complications and end point events.