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ε-AChR和γ-AChR在神经肌肉疾病中的表达变化 被引量：2

Theε-AChR andγ-AChR Expression Changes in Neuromuscular Disease
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摘要 烟碱型乙酰胆碱受体(nAChR)分布于神经肌肉接头突触后膜上,分为ε–AChR和γ–AChR两种亚型。周围神经损伤和重症肌无力等神经肌肉疾病时,这两种亚型存在着亚基转换。它们在突触后膜上的表达转换可用作评价神经肌肉功能疾病恢复的指标。 Objective Nicotinic acetylcholine receptors （nAChR） distribute in nerve muscle joints on the postsyn- aptic membrane, which may be devided into two two subtypes： the ε-AChR and γ -AChR. The neuromuscular disea- ses such as peripheral nerve injury and myasthenia gravis. The two subtypes exist subunite transformation,which can be used as evaluation index of neuromuscular disease function in postsynaptie membrane.
作者 易晓东 杨胜波
机构地区 遵义医学院人体解剖教研室
出处 《四川解剖学杂志》 2013年第2期58-60,63,共4页 Sichuan Journal of Anatomy
基金 贵州省科技厅攻关项目(No.C-748)
关键词 ε–AChR γ–AChR 神经肌接头 周围神经损伤 重症肌无力 ε-AChR γ-AChR Neuromuscular connection Peripheral nerve injury Myasthenia gravis
分类号 R746.1 [医药卫生—神经病学与精神病学]
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参考文献25

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二级参考文献9

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共引文献18

同被引文献28

  • 1吴怀国,陈荣志,许文华,杨毅,任明山.乙酰胆碱受体α亚基125-147肽段制作实验性重症肌无力动物模型的研究[J].临床神经病学杂志,2006,19(5):368-370. 被引量：9
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引证文献2

二级引证文献3

四川解剖学杂志
2013年 第2期

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