0.3%尼泊金乙酯对尿液中尿酸及清蛋白检测结果的影响

Effect of 0.3% ethylparaben on the test results of uric acid and albumin in urine

目的探讨0.3%尼泊金乙酯对尿液中尿酸(UA)及清蛋白(U-MA)检测结果是否有影响。方法收集新鲜尿标本,加入0.3%尼泊金乙酯前检测UA、U-MA;按照100mL尿液中加入0.5mL 0.3%尼泊金乙酯室温保存尿液0h、4h、8h、12h、24h,分别检测尿液中的UA、U-MA,将检测结果与加入0.3%尼泊金乙酯前检测结果进行统计学分析。结果新鲜尿标本加入0.3%尼泊金乙酯前检测UA、U-MA结果与0.3%尼泊金乙酯保存尿标本0h、4h、8h、12h、24h后检测UA、U-MA的结果呈正相关,相关性良好(r>0.975),且差异无统计学意义(P>0.05)。结论 0.3%尼泊金乙酯对尿液中UA、U-MA检测结果无影响,可作为部分尿液检验项目的防腐剂。

Objective To explore whether 0.3% ethylparaben would affect the test results of uric acid （UA） and albumin （U-MA） in urine. Methods Fresh urine specimens were collected,and the UA and U-MA were instantly detected before adding the 0.3% ethylparaben. Per 100 mL urine was added 0.5 mL 0.3% ethylparaben,stored at room temperature. At 0h,4h,8h,12h,and 24h,the UA and U-MA in the urine were detected respectively. The test results of UA and U-MA detected before and after adding the 0.3 % ethylparaben were statistically analyzed. Results The test results of UA and U-MA in fresh urine specimens which were instantly detected before adding the 0.3 % ethylparaben were positively correlated with the test results of UA and U-MA in the urine which was storaged by 0. 3% ethylparaben at room temperature, and the correlation was good（r〉0. 975）. There was no significant difference between them （P〉0.05）. Conclusion 0.3% ethylparaben has no effect on the test results of UA and U-MA in u- rine,and it can be used as the urine preservatives.