黔南及黔东南虫媒病毒人群血清流行病学调查

Seroepidemiological survey of arbovirus among people in southern and southeastern Guizhou

目的了解黔南及黔东南部分虫媒病毒人群血清抗体阳性分布。方法2012年8月，选取在当地连续居住1年以上、年龄18～40岁的自愿健康人群，用间接免疫荧光试验法，调查马亚罗（MAY）、辛德比斯（SIN）、基孔肯雅（CHIK）、盖他（GET）、流行性乙型脑炎（JE）、登革热Ⅲ型（DEN-3）、流行性出血热（EHF）和森林脑炎（TBE）病毒在黔南及黔东南人群中的阳性分布。结果共检测血清标本502份，111份至少有1种病毒抗体阳性，抗体阳性检出率最高的是JE，阳性率为12．15％；其次为MAY，阳性率为10．28％；TBE未检出抗体阳性血清。居住时间、居住地性质和地区分布对抗体的阳性分布影响较为显著。结论黔南和黔东南可能是多种虫媒病毒病的自然疫源地。

Objective To explore the positive distribution of serum antibody in people infected by arbovirus in southern and southeastern Guizhou. Methods In August 2012, healthy volunteers aged between 18 and 40 years old who lived in the locality for more than one year were chosen to receive the indirect immunofluoresceee test in order to investigate the positive distribution of MAY, SIN, CHIK, GET, JE, DEN-3, EHF, and TBE virus among people in southern and southeastern Guizhou. Results Totally 502 samples of blood serum were obtained and detected. In 111 specimens, there was at least one kind of positive antibody of the virus above. The positive antibody detection rate of JE was the highest （ 12.15% ）, and the next was MAY （ 10.28% ）. The positive serum with TBE antibody was not found. The distribution of positive antibody was significantly influenced by the length of residence, the character of dwelling region, and endemic distribution. Conclusion Southern and southeastern Guizhou might be the natural foci of many arbovirus diseases.