中山市A组轮状病毒感染的流行病学特征

Epidemiological characteristics of group A rotavirus infection in Zhongshan city

目的 了解中山地区A组轮状病毒感染情况和流行病学特征.方法 应用免疫层析双抗体夹心法对疑似A组轮状病毒感染的患儿新鲜粪便标本进行A组轮状病毒检测,并进行流行病学分析.结果 969例标本中168例A组轮状病毒抗原检测阳性,总阳性率为,17.34%,男女比例为2.23：1.00.6～12个月年龄段婴幼儿最为易感.在该地区秋冬季节是A组轮状病毒感染的高发季节,高峰在11～12月.结论 A组轮状病毒是中山地区婴幼儿腹泻的重要病原体,对A组轮状病毒进行监测对其诊断和合理治疗及流行情况的监控具有重大意义.

Objective To understand group A rotavirus infection and epidemiological characteristics in Zhongshan region. Methods Double-antibody sandwich immunoassay was employed to detect the group A rotavirus in fresh stool specimens of children suspected to be infected with group A rotavirus. Results Among 969 specimens, 168 were found group A rotavirus antigen positive, with 17.34% of total positive rate and 2.23 ： 1.00 of male to female ratio. Infants aged 6 to 12 months were the most susceptible. Autumn and winter in the area were the high-occurrence seasons of group A rotavirus infection, The peak months were in December and November. Conclusion Group A rotavirus is an important pathogen of diarrhea in infant and children, and its detection is of great significance for diagnosis, appropriate treatment and prevalence monitor.