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血清sB7-H4检测在胃癌诊断中的价值 被引量：1

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摘要 目的探讨血清可溶性B7-H4(sB7-H4)检测对胃癌的诊断价值。方法采用酶联免疫吸附测定(ELISA)法检测50例胃癌患者、30例慢性胃炎患者和30例健康志愿者血清sB7-H4水平,并分析胃癌患者血清sB7-H4水平与临床病理参数的关系。结果胃癌组血清sB7-H4浓度为(48.26±12.32)ng/mL,显著高于胃炎组[(33.53±10.29)ng/mL]和对照组[(28.40±9.24)ng/mL],差异均有统计学意义(P<0.05)。胃癌组患者血清sB7-H4浓度与肿瘤TNM分期、分化程度及有无淋巴结转移相关(P<0.05),但与年龄、性别、肿瘤大小及病理组织类型无关。结论 sB7-H4与胃癌发生、发展及转移相关,可作为胃癌诊疗的潜在血清标志物。
作者 胡建慧 陈忠 毛飞
机构地区 镇江市中医院检验科 苏州永鼎医院检验科 江苏大学基础医学与医学技术学院
出处 《国际检验医学杂志》 CAS 2013年第21期2920-2922,共3页 International Journal of Laboratory Medicine
关键词 胃肿瘤 酶联免疫吸附测定 血清 可溶性B7-H4
分类号 R446.1 [医药卫生—诊断学] R735.2 [医药卫生—肿瘤]
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参考文献19

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二级参考文献55

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共引文献54

同被引文献13

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国际检验医学杂志
2013年 第21期

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