不良妊娠与TORCH感染关系的研究

A Study on the Relatonship Between Adverse Fetation and TORCH Series Infection

目的 :对不良妊娠分娩史者进行TORCH检测 ,探讨妊娠期TORCH感染与胎儿发育异常及先天缺陷的关系。方法 :对 5 4例有不良妊娠分娩史的妇女进行血清TORCH系列检测 ,与无不良妊娠分娩史的孕妇进行对照。结果 :实验组血清TORCH系列IgG、IgM抗体阳性率明显高于对照组 (P <0 0 1)。结论 :人类巨细胞病毒、弓形体风疹病毒感染严重者 ,均可通过胎盘传播给胎儿 ,导致孕妇流产、死胎、死产、胎儿畸形、发育迟缓 ,因此必须引起重视 。

Objective:This paper investigated the relationshup between TORCH infection and abnormal fetal growth as well as congenital defects.Methods:sera tests for TORCH were carried out in 54 pregnant women with abnormal fetation history and in 54 normal gravidas using immunological techniques.Results:The positive incidence of antibodies against the TORCH series in the patient group were significantly higher than that of the controls(P<0.001).Conclusion:Cytomegalovirus,Toxoplasma and Rubella virus can pass through the placenta from infected mother to fetus and result in serious outcome,such as abortion,dead fetus,still-birth,fetal malformation and fetal growth retardation,suggestion that attention be paid and active treatment be given to these gravidas possibly infected by TORCH.