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血管平滑肌细胞增殖相关microRNA的研究进展 被引量：2

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摘要 microRNAs（miRNAs）是1993年Ambro教授在研究线虫发育时序时最先发现的。miRNAs与其靶mRNA分子组成一个复杂的调控网络．参与机体发育、于细胞分化、心血管疾病、肿瘤、
作者 朱明燕 莫中成 曾高峰
机构地区 南华大学医学院 南华大学医学院组胚教研室 南华大学医学院附属第二医院
出处 《实用医学杂志》 CAS 北大核心 2013年第21期3610-3612,共3页 The Journal of Practical Medicine
基金 国家自然科学基金资助项目(编号:81100211) 南华大学博士启动基金项目(编号:2012XQD27)
关键词 血管平滑肌细胞增殖 MICRORNA MIRNAS 发育时序 心血管疾病 调控网络 分子组成 MRNA
分类号 R363 [医药卫生—病理学]
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参考文献20

  • 1Mendell J T, Olson E N. MicroRNAsin stress signaling and human disease[J]. Cell, 2012,148(6):1172-1187.
  • 2Qin S, Zhang C. MicroRNAs in vascu-lar disease[J], J Cardiovasc Pharma-col, 2011,57(1):8-12.
  • 3Virtue A, Mai J, Yin Y, et al. Struc-tural evidence of anti-atherogenic mi-croRNAs[J]. Front Biosci(LandmarkEd), 2011,16:3133-3145.
  • 4Madrigal-Matute J, Hotllan N, ArandaJ F, et al. MicroRNAs and atheroscle-rosis[J]. Curr Atheroscler Rep,2013,15(5):322.
  • 5Jakob P, Landmesser U. Role of mi-croRNAs in stem/progenitor cells andcardiovascular repair[J]. CardiovascRes, 2011,93(4):614-622.
  • 6Cheng Y,Liu X, Yang J,et al. Mi-croRNA-145, a novel smooth musclecell phenotypic marker and modulator,controls vascular neointimal lesion for-mation[J]. Circ Res, 2009,105(2):158-166.
  • 7Hergenreider E,Heydt S,Treguer K,et al. Atheroprotebtive communicationbetween endothelial cells and smoothmuscle cells through miRNAs[J]. NatCell Biol, 2012,14(3):249-256.
  • 8Cordes K R, Sheehy N T,White MP, et al. miR-145 and miR-143 regu-late smooth muscle cell fate and plas-ticity[J]. Nature, 2009,460(7256):705-710.
  • 9Boettger T,Beetz N, Kostin S,et al.Acquisition of the contractile phenotypeby murine arterial smooth muscle cellsdepends on the Mirl43/145 gene clus-ter[J]. J Clin Invest, 2009,119(9):2634-2647.
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同被引文献27

  • 1唐朝枢,齐永芬.关注血管钙化发病新机制的研究[J].中国医学前沿杂志（电子版）,2010,2(3):5-8. 被引量：10
  • 2Goettsch C, Rauner M, Pacyna N, et al. miR-125b regulates cal- cification of vascular smooth muscle cells [ J ]. Am J Pathol, 2011, 179(4) : 1594 - 1600.
  • 3Wang H, Peng W, Ouyang X, et al. Reduced eirculating mi- R-15b is eorrelated with phosphate metabolism in patients with end-stage renal disease on maintenance hemodialysis [ J ]. Ren Fail, 2012, 34(6) : 685 -690.
  • 4Du Y, Gao C, Liu Z, et al. Upregulation of a disintegrin and metalloproteinase with thronospondin motifs-7 by miR-29 repression mediates vascular smooth muscle calcification [ J 1. Arterioscler Thromb Vase Biol, 2012, 32 ( 11 ) : 2580 - 2588.
  • 5Johnson RC, Leopold JA, Loscalzo J. Vascular calcification: pathobiological mechanisms and clinical implications [ J ]. Circ Res, 2006, 99(10): 1044- 1159.
  • 6Pasquinelli AE, Ruvkun G. Control of developmental timing by micromas and their targets[ J]. Annu Rev Cell Dev Biol, 2002, 18:495 -513.
  • 7Cui RR, Li SJ, Liu LJ, et al. MieroRNA-204 regulates vascular smooth muscle cell calcification in vitro and in vivo [ J ]. Cardiovasc Res, 2012, 96(2) : 320 -329.
  • 8Qiao W, Chen L, Zhang M. MicroRNA-205 regulates the calcifi- cation and osteoblastie differentiation of vascular smooth muscle cells[J]. Cell Physiol Biochem, 2014, 33(6) : 1945 -1953.
  • 9Mackenzie NC, Staines KA, Zhu D, et al. miRNA-221 and mi- RNA-222 synergistically function to promote vascular calcification [J]. Cell Biochem Funct, 2014, 32(2): 209-216.
  • 10Rangrez AY, M' Baya-Moutoula E, Metzinger-Le Meuth V, et al. Inorganic phosphate accelerates the migration of vascular smooth muscle cells : evidence for the involvement of miR-223 [ J ]. PLoS One, 2012, 7(10) : e47807.

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实用医学杂志
2013年 第21期

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