脏腑兼病证动物模型研究

Animal Model Studies of Viscera Symptom Complex

脏腑兼病证动物模型目前主要有肝郁脾虚证、脾肾阳虚证、少阴病心肾阳虚水停证、“肺与大肠相表里”理论等动物模型的研究。这类研究为脏腑兼病学说的发展开辟了一条新路。但在某些方面还有待进一步完善和提高 ,如在模型方法的设计上应尽可能靠近中医传统病因 ,在症状诊断上要制定符合动物特性的统一的脏腑兼病证诊断标准 ,在客观指标的确定上应根据中医理论选择与脏腑兼病学说相关性更高、特异性更强的实验指标 ,在反证方药的选择上应力求标准化。

At present,the main animal models of viscera symptom complex are:Stagnation of the liver qi and deficiency of the spleen,insufficiency of both the spleen and the kidney,insufficiency of both the heart and the kidney and retention of water in shaoyin disease and the theory of “the lung and the large intestine being interior exteriorly related”,their studies open a new way for the development of viscera symptom complex theory,however,further improvement and perfection should be made in some points,e.g.,the model design,diagnostic standard of viscera symptom complex,definition of objective quota and standardization on choosing prescription and drugs in counterevidence.