幕上海绵状血管瘤所致癫疒间的手术预后及其相关影响因素分析

Analysis of surgical outcomes and relevant factors for supratentorial cavernous angioma-associated epilepsy

目的探讨颅内海绵状血管瘤（CCA）所致癫癎的手术效果及其相关影响因素。方法回顾性分析49例CCA所致癫癎病人的手术效果。并分析年龄、性别、病灶位置、病灶大小、病程、癫癎发作类型与手术预后的相关性。结果术后随访1~4年，EngelI级39例（79．6％），EngelII～Ⅳ级10例（20．4％）。统计学分析显示：病灶〈1．5cm、病程≤1年及部分性癫癎发作的病人手术预后较好（P〈0．05），而年龄、性别、病灶位置与手术预后没有明显的相关性（P〉O．05）。结论CCA所致癫癎的手术效果理想，病灶大小、病程和癫癎发作类型与手术预后相关。

Objective To discuss surgical outcomes and relevant factors for intracranial cavernous angioma （CCA） -associated epilepsy. Methods Surgical outcomes of 49 patients with epilepsy caused by CCA were analyzed retrospectively. The correlations of age, gender, lesion location, lesion size, disease duration and epileptic attack type to surgical prognosis were evaluated statistically. Results During a follow-up period of 1 to 4 years, Engel class I was achieved in 39 patients （79.6%） and Engel class II to IV in 10 （20.4%）. The statistical analysis showed that the better surgical outcomes were achieved in patients with lesion size less than 1.5 cm, disease duration equal to and less than 1 year and partial epileptic attack （P 〈 0.05）, while there was no obvious correlation of age, gender and lesion location to the surgical outcome （P 〉 0.05）. Conclusions The surgical outcome of CCA-associated epilepsy is favorable. The lesion size, illness duration and epileptic attack type correlate significantly with surgical outcome.